LMAN1L

Across TCGA pan-cancer cohorts, LMAN1L RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of LMAN1L’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where LMAN1L RNA is repressed in tumor relative to normal tissue. In most cancer types LMAN1L is over-expressed in tumor, although a few such as STAD and LUAD show the opposite, repressed pattern.

STAD, LUAD, and KIRC are the cancer types where LMAN1L tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LMAN1L RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	Male	All	−0.072	.024	4	view →
LUAD	All	II,III,IV	−0.013	.031	3	view →
KIRC	All	All	+0.008	.030	3	view →
ESCA	All	II,III,IV	−0.070	.019	2	view →
LUSC	All	All	+0.047	.017	1	view →
BLCA	All	IV	−0.030	.036	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

LMAN1L–STAD

Open the STAD breakdown →