LIPH

Across TCGA cell cohorts, LIPH RNA expression is significantly associated with the go_rna of many other GO terms, with 4,296 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible LIPH-associated GO terms across cancer lineages are Maintenance of blood-brain barrier, Regulation of potassium ion import, and Negative regulation of T cell mediated cytotoxicity. Each is linked with LIPH in more than 10 cancer types. Because this analysis shows association rather than direction, both LIPH-to-partner and partner-to-LIPH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maintenance of blood-brain barrier grouped by LIPH-low versus LIPH-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPH→partner) and Y-score (partner→LIPH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Maintenance of blood-brain barrier →	+0.174	+1.173	<.001	.001	3	11
STOMACH	Regulation of potassium ion import →	+0.265	+3.188	<.001	<.001	3	11
PANCREAS	Negative regulation of T cell mediated cytotoxicity →	+1.790	+2.792	<.001	<.001	3	11
OESOPHAGUS	Negative regulation of actin filament polymerization →	+0.171	+2.744	<.001	<.001	3	11
OVARY	Protein localization to plasma membrane →	+0.062	+1.649	<.001	.003	3	10
PANCREAS	Establishment of endothelial intestinal barrier →	+0.170	+2.618	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,296 associations by consensus.

Maintenance of blood-brain barrier by LIPH expression — SKIN

Explore this box plot interactively →