LIPE

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LIPE RNA expression is significantly associated with the protein abundance of many other proteins, with 18,453 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LIPE-associated proteins across cancer lineages are LIPE_S855, PDIA4, and PLIN1_S382. Each is linked with LIPE in more than 6 cancer types. Because this analysis shows association rather than direction, both LIPE-to-partner and partner-to-LIPE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIPE versus LIPE_S855 in BRCA, with a Pearson correlation of 0.80.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPE→partner) and Y-score (partner→LIPE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCALIPE_S855 →+1.269+1.607<.001<.00137
CCRCCPDIA4 →-0.459-0.333<.001.00235
COADPLIN1_S382 →+1.978+0.839<.001<.00135
GBMFNDC3B →-0.365-0.535<.001<.00135
CCRCCSEPTIN4 →+0.559+0.493<.001<.00135
OVCNRIP1 →+0.760+1.094<.001.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 18,453 associations by consensus.

LIPE vs LIPE_S855 — BRCA

Per-sample scatter of LIPE vs LIPE_S855 in BRCA (Pearson r = 0.80).

Explore this scatter interactively →

Exploration