LIPC

Across TCGA patient cohorts, LIPC RNA expression is significantly associated with the protein abundance of many other proteins, with 8,984 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LIPC-associated proteins across cancer lineages are STRBP, SGCD, and MTPAP. Each is linked with LIPC in more than 3 cancer types. Because this analysis shows association rather than direction, both LIPC-to-partner and partner-to-LIPC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIPC versus STRBP in LSCC, with a Pearson correlation of -0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LIPC→partner) and Y-score (partner→LIPC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	STRBP →	-0.597	-0.296	<.001	.001	3	4
BRCA	SGCD →	+0.838	+0.256	<.001	<.001	3	4
BRCA	MTPAP →	-0.350	-0.215	<.001	<.001	3	3
BRCA	NACC1 →	-0.229	-0.225	<.001	<.001	3	3
LSCC	NCAPD2 →	-0.488	-0.294	<.001	<.001	3	3
OV	NCAPG →	-0.406	-0.461	.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,984 associations by consensus.

LIPC vs STRBP — LSCC

Explore this scatter interactively →