LINC02448

Across TCGA pan-cancer cohorts, LINC02448 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated LINC02448 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher LINC02448 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC02448 expression acts as an unfavorable survival marker, although some lineages such as LUSC and ESCA show a favorable association.

LUAD, MESO, and KIRC are the cancer types where LINC02448 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Tertile	II,III,IV	0.576	0.746	.001	85	view →
MESO	OS	Tertile	III,IV	0.126	0.589	<.001	81	view →
KIRC	DFS	Tertile	All	0.219	0.644	.001	54	view →
SKCM	OS	Tertile	III,IV	0.238	0.706	<.001	42	view →
BRCA	DFS	Tertile	All	0.140	1.000	.001	36	view →
THYM	DFS	Tertile	All	0.075	0.885	<.001	36	view →
UCEC	OS	Tertile	III,IV	0.647	0.837	.011	24	view →
LUSC	DFS	Quartile	II,III,IV	0.734	0.576	.019	13	view →
ESCA	DFS	Median	III,IV	0.551	0.334	.028	13	view →
GBM	OS	Tertile	All	0.418	0.166	.010	12	view →
OV	OS	Tertile	III,IV	0.534	0.305	.042	12	view →
READ	OS	Tertile	IV	0.555	0.891	.018	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

LINC02448–LUAD (OS)

Open the LUAD breakdown →