Across TCGA pan-cancer cohorts, LINC02448 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of LINC02448’s most consistent transcriptional readouts.
The strongest signal is observed in lung adenocarcinoma (LUAD), where LINC02448 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC02448 is over-expressed in tumor.
LUAD and LUSC are the cancer types where LINC02448 tumor–normal differential expression is most reproducible.