long intergenic non-protein coding RNA 2448Genealiases: []
Q-omics provides the consensus-scored LINC02448 profile across patient tissues and cancer cell-line models. LINC02448 expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in LUAD. Among the 18 cancer types available for tumor–normal comparison, LINC02448 is differentially expressed in 2, with the highest sampling consensus in LUAD. Additionally, LINC02448 RNA expression shows 6,088 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight LUAD, and STAD as cancer lineages where LINC02448 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC02448 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC02448 survival associations across molecular data types. LINC02448 RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC02448 RNA expression–survival associations across cancer types. High LINC02448 expression shows unfavorable associations in LUAD, MESO, KIRC, SKCM, BRCA and THYM. The LUAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify LUAD as the clearest survival context for LINC02448 RNA expression.
This table summarizes LINC02448 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in LUAD for RNA.
This table ranks reproducible tumor–normal expression differences for LINC02448. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC02448 shows higher tumor expression in LUAD and LUSC. The LUAD box plot shows higher LINC02448 RNA expression in tumor versus normal tissue (log2 FC = +0.088, t-test p = .019).
This table shows molecular features associated with LINC02448 in patient tissues and cancer cell lines. In patient samples, LINC02448 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
