LINC02273

Across TCGA pan-cancer cohorts, LINC02273 RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated LINC02273 data layer.

The strongest signal is observed in skin cutaneous melanoma (SKCM), where higher LINC02273 RNA is associated with better overall survival. In most high-consensus cancer types, elevated LINC02273 expression acts as an unfavorable survival marker, although some lineages such as SKCM and CESC show a favorable association.

SKCM, LUSC, and CESC are the cancer types where LINC02273 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
SKCM	OS	Tertile	All	0.460	0.278	.001	51	view →
LUSC	OS	Quartile	II,III,IV	0.285	0.647	.001	46	view →
CESC	DFS	Tertile	All	0.798	0.669	.012	46	view →
UCEC	DFS	Tertile	All	0.878	0.791	.008	44	view →
LUAD	DFS	Median	All	0.734	0.599	<.001	43	view →
LGG	DFS	Median	All	0.667	0.791	<.001	38	view →
GBM	OS	Median	All	0.209	0.313	.008	33	view →
ACC	DFS	Median	III,IV	0.632	0.291	.009	31	view →
ESCA	DFS	Tertile	III,IV	0.530	0.244	.004	26	view →
MESO	DFS	Median	All	0.449	0.279	.003	23	view →
BRCA	DFS	Median	II,III,IV	0.615	0.442	.003	22	view →
UVM	OS	Tertile	All	0.396	0.834	.005	22	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

LINC02273–SKCM (OS)

Open the SKCM breakdown →