long intergenic non-protein coding RNA 2273Genealiases: []
Q-omics provides the consensus-scored LINC02273 profile across patient tissues and cancer cell-line models. LINC02273 expression is associated with patient survival in 23 of 34 cancer types, with the highest sampling consensus in SKCM. Among the 18 cancer types available for tumor–normal comparison, LINC02273 is differentially expressed in 8, with the highest sampling consensus in KIRC. Additionally, LINC02273 RNA expression shows 12,804 significant protein co-abundance associations, with the highest sampling consensus in LSCC. Together, these results highlight SKCM, KIRC, and LSCC as cancer lineages where LINC02273 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC02273 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC02273 survival associations across molecular data types. LINC02273 RNA expression shows survival associations in the most cancer types (23). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC02273 RNA expression–survival associations across cancer types. High LINC02273 expression shows unfavorable associations in LUSC and LGG, but favorable associations in SKCM, CESC, UCEC and LUAD. The SKCM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify SKCM as the clearest survival context for LINC02273 RNA expression.
This table summarizes LINC02273 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC02273. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC02273 shows lower tumor expression in LUSC and KICH and higher tumor expression in KIRC, HNSC, STAD and BRCA. The KIRC box plot shows higher LINC02273 RNA expression in tumor versus normal tissue (log2 FC = +0.531, t-test p < 0.001).
This table shows molecular features associated with LINC02273 in patient tissues and cancer cell lines. In patient samples, LINC02273 shows the broadest associations at the RNA and protein expression levels, with LSCC recurring as the lineage with the largest associated feature set.
