LINC02270

Across TCGA pan-cancer cohorts, LINC02270 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated LINC02270 data layer.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher LINC02270 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC02270 expression acts as an unfavorable survival marker, although some lineages such as BLCA and DLBC show a favorable association.

LIHC, BLCA, and UVM are the cancer types where LINC02270 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Tertile	II,III,IV	0.203	0.447	.001	96	view →
BLCA	OS	Tertile	All	0.792	0.335	.017	54	view →
UVM	OS	Tertile	All	0.302	0.710	.015	24	view →
LUAD	OS	Tertile	IV	0.114	0.560	.038	18	view →
ACC	DFS	Tertile	III,IV	0.265	0.691	.026	18	view →
PAAD	DFS	Tertile	All	0.200	0.370	.041	9	view →
DLBC	DFS	Tertile	All	1.000	0.699	.036	6	view →
SKCM	OS	Tertile	III,IV	0.553	0.723	.041	6	view →
STAD	OS	Quartile	IV	0.838	0.322	.047	3	view →
COAD	OS	Tertile	II,III,IV	0.280	0.577	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

LINC02270–LIHC (DFS)

Open the LIHC breakdown →