LINC02145

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC02145 mutation is significantly associated with the RNA expression of many other genes, with 2,661 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC02145-associated genes across cancer lineages are MIR541, MIR6893, and AQP7P5. Each is linked with LINC02145 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC02145-to-partner and partner-to-LINC02145 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR541 grouped by LINC02145-low versus LINC02145-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC02145→partner) and Y-score (partner→LINC02145) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMMIR541 →+0.316+4.147<.001.00832
SKCMMIR6893 →+0.324+3.622<.001.00531
SKCMAQP7P5 →+0.071+3.302.002.00931
LGGUSP9YP10 →+0.049+7.977<.001.00731
LUSCTTTY1B →+0.049+7.924<.001.00831
LUSCRNU6-755P →+0.295+7.924<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,661 associations by consensus.

MIR541 by LINC02145 expression — SKCM

Box plot of MIR541 in LINC02145-low vs LINC02145-high samples in SKCM.

Explore this box plot interactively →

Exploration