long intergenic non-protein coding RNA 1777Genealiases: []
Q-omics provides the consensus-scored LINC01777 profile across patient tissues and cancer cell-line models. LINC01777 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, LINC01777 is differentially expressed in 6, with the highest sampling consensus in BRCA. Additionally, LINC01777 RNA expression shows 6,378 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight UVM, BRCA, and STAD as cancer lineages where LINC01777 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC01777 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC01777 survival associations across molecular data types. LINC01777 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC01777 RNA expression–survival associations across cancer types. High LINC01777 expression shows unfavorable associations in CESC, GBM and STAD, but favorable associations in UVM, LUAD and BRCA. The UVM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify UVM as the clearest survival context for LINC01777 RNA expression.
This table summarizes LINC01777 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for LINC01777. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC01777 shows lower tumor expression in BRCA, KICH, KIRC and KIRP and higher tumor expression in PRAD and LIHC. The BRCA box plot shows higher LINC01777 RNA expression in normal versus tumor tissue (log2 FC = −0.096, t-test p < 0.001).
This table shows molecular features associated with LINC01777 in patient tissues and cancer cell lines. In patient samples, LINC01777 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
