LINC01777

Across TCGA pan-cancer cohorts, LINC01777 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of LINC01777’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC01777 RNA is repressed in tumor relative to normal tissue. In most cancer types LINC01777 is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

BRCA, KICH, and KIRC are the cancer types where LINC01777 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in LINC01777 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.096	<.001	4	view →
KICH	All	All	−0.021	.008	4	view →
KIRC	Male	All	−0.018	<.001	3	view →
PRAD	All	All	+0.014	.028	2	view →
LIHC	All	III,IV	+0.023	.031	1	view →
KIRP	All	All	−0.010	.039	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

LINC01777–BRCA

Open the BRCA breakdown →