LINC01553

Across TCGA cell cohorts, LINC01553 mutation is significantly associated with the mutation status of many other genes, with 1,522 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible LINC01553-associated genes across cancer lineages are PRODH2, OR2W1, and CD200R1L. Each is linked with LINC01553 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC01553-to-partner and partner-to-LINC01553 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRODH2 grouped by LINC01553-low versus LINC01553-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC01553→partner) and Y-score (partner→LINC01553) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PRODH2 →	+2.893	+3.222	.003	.003	1	2
LARGE_INTESTINE	OR2W1 →	+3.799	+3.329	.005	.005	1	2
LARGE_INTESTINE	CD200R1L →	+5.215	+4.159	<.001	<.001	1	2
LARGE_INTESTINE	STRAP →	+3.799	+3.329	.005	.005	1	2
LARGE_INTESTINE	PRSS21 →	+2.893	+3.222	.003	.003	1	2
LARGE_INTESTINE	MPP5 →	+2.367	+3.372	.002	.002	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,522 associations by consensus.

PRODH2 by LINC01553 expression — LARGE_INTESTINE

Explore this box plot interactively →