LINC01553

Across TCGA pan-cancer cohorts, LINC01553 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated LINC01553 data layer compared with 2 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher LINC01553 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC01553 expression acts as an unfavorable survival marker, although some lineages such as COAD and SKCM show a favorable association.

UCEC, BRCA, and COAD are the cancer types where LINC01553 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	0.509	0.753	<.001	98	view →
BRCA	DFS	Quartile	III,IV	0.584	0.841	<.001	66	view →
COAD	DFS	Quartile	IV	0.764	0.290	.001	33	view →
SKCM	OS	Tertile	All	0.874	0.768	.018	30	view →
THYM	OS	Tertile	II,III,IV	0.778	0.982	.020	21	view →
TGCT	OS	Tertile	III,IV	0.501	1.000	.014	18	view →
READ	OS	Median	II,III,IV	0.852	0.987	.037	7	view →
LAML	DFS	Median	All	0.404	0.676	.005	6	view →
LUAD	DFS	Median	IV	0.638	0.375	.041	4	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

LINC01553–UCEC (OS)

Open the UCEC breakdown →