long intergenic non-protein coding RNA 1498Genealiases: []
Q-omics provides the consensus-scored LINC01498 profile across patient tissues and cancer cell-line models. LINC01498 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in HNSC. Among the 18 cancer types available for tumor–normal comparison, LINC01498 is differentially expressed in 8, with the highest sampling consensus in HNSC. Additionally, LINC01498 RNA expression shows 6,722 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight HNSC, and STAD as cancer lineages where LINC01498 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC01498 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC01498 survival associations across molecular data types. LINC01498 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC01498 RNA expression–survival associations across cancer types. High LINC01498 expression shows unfavorable associations in KIRC, LIHC, COAD and ACC, but favorable associations in HNSC and SKCM. The HNSC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .005). Together, the overview and detailed table identify HNSC as the clearest survival context for LINC01498 RNA expression.
This table summarizes LINC01498 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 8. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC01498. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC01498 shows lower tumor expression in THCA and higher tumor expression in HNSC, KICH, BLCA, STAD and LIHC. The HNSC box plot shows higher LINC01498 RNA expression in tumor versus normal tissue (log2 FC = +0.019, t-test p = .029).
This table shows molecular features associated with LINC01498 in patient tissues and cancer cell lines. In patient samples, LINC01498 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
