long intergenic non-protein coding RNA 1258Genealiases: []
Q-omics provides the consensus-scored LINC01258 profile across patient tissues and cancer cell-line models. LINC01258 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, LINC01258 is differentially expressed in 9, with the highest sampling consensus in THCA. Additionally, LINC01258 RNA expression shows 10,688 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight UCEC, THCA, and TGCT as cancer lineages where LINC01258 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC01258 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC01258 survival associations across molecular data types. LINC01258 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC01258 RNA expression–survival associations across cancer types. High LINC01258 expression shows unfavorable associations in LIHC, KIRC and TGCT, but favorable associations in UCEC, HNSC and ESCA. The UCEC Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .002). Together, the overview and detailed table identify UCEC as the clearest survival context for LINC01258 RNA expression.
This table summarizes LINC01258 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 9. The strongest signals are observed in THCA for RNA.
This table ranks reproducible tumor–normal expression differences for LINC01258. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC01258 shows lower tumor expression in THCA, KICH and KIRC and higher tumor expression in COAD, READ and LUSC. The THCA box plot shows higher LINC01258 RNA expression in normal versus tumor tissue (log2 FC = −0.068, t-test p < 0.001).
This table shows molecular features associated with LINC01258 in patient tissues and cancer cell lines. In patient samples, LINC01258 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
