LINC01258

Across TCGA pan-cancer cohorts, LINC01258 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated LINC01258 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher LINC01258 RNA is associated with better overall survival. In most high-consensus cancer types, elevated LINC01258 expression acts as an unfavorable survival marker, although some lineages such as UCEC and HNSC show a favorable association.

UCEC, HNSC, and LIHC are the cancer types where LINC01258 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Quartile	II,III,IV	0.876	0.433	.002	94	view →
HNSC	DFS	Median	All	0.771	0.654	.002	85	view →
LIHC	DFS	Tertile	All	0.286	0.470	<.001	64	view →
KIRC	DFS	Median	All	0.747	0.834	.002	58	view →
ESCA	OS	Tertile	All	0.634	0.348	.002	42	view →
TGCT	DFS	Median	All	0.729	0.897	.003	38	view →
LUAD	DFS	Tertile	IV	0.398	0.803	.004	36	view →
OV	DFS	Median	IV	0.320	0.534	.007	16	view →
BRCA	DFS	Tertile	II,III,IV	0.959	0.933	.033	14	view →
PRAD	DFS	Quartile	All	0.980	0.892	.001	10	view →
THCA	OS	Tertile	IV	0.720	1.000	.004	9	view →
GBM	DFS	Tertile	All	0.205	0.393	.025	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

LINC01258–UCEC (OS)

Open the UCEC breakdown →