LINC00858

Across TCGA pan-cancer cohorts, LINC00858 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated LINC00858 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher LINC00858 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00858 expression acts as an unfavorable survival marker, although some lineages such as SKCM and READ show a favorable association.

KICH, LIHC, and SKCM are the cancer types where LINC00858 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	DFS	Tertile	All	0.548	0.922	<.001	81	view →
LIHC	OS	Tertile	All	0.575	0.740	<.001	54	view →
SKCM	OS	Quartile	All	0.855	0.713	.006	46	view →
KIRC	OS	Tertile	All	0.725	0.838	.002	36	view →
UVM	DFS	Median	All	0.465	0.914	.005	32	view →
KIRP	DFS	Quartile	All	0.430	0.656	.004	31	view →
CESC	DFS	Tertile	All	0.741	0.841	.010	24	view →
COAD	DFS	Quartile	III,IV	0.557	0.869	.006	17	view →
LUSC	OS	Median	III,IV	0.242	0.539	.001	16	view →
SARC	OS	Tertile	All	0.649	0.782	.004	15	view →
READ	OS	Tertile	II,III,IV	0.801	0.238	.001	15	view →
PCPG	OS	Quartile	All	0.714	1.000	<.001	15	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

LINC00858–KICH (DFS)

Open the KICH breakdown →