long intergenic non-protein coding RNA 858Genealiases: CRCAL-2 · LNMAT2
Q-omics provides the consensus-scored LINC00858 profile across patient tissues and cancer cell-line models. LINC00858 expression is associated with patient survival in 19 of 34 cancer types, with the highest sampling consensus in KICH. Among the 18 cancer types available for tumor–normal comparison, LINC00858 is differentially expressed in 12, with the highest sampling consensus in COAD. Additionally, LINC00858 RNA expression shows 11,484 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight KICH, COAD, and THYM as cancer lineages where LINC00858 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00858 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00858 survival associations across molecular data types. LINC00858 RNA expression shows survival associations in the most cancer types (19). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00858 RNA expression–survival associations across cancer types. High LINC00858 expression shows unfavorable associations in KICH, LIHC, KIRC, UVM and KIRP, but favorable associations in SKCM. The KICH Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify KICH as the clearest survival context for LINC00858 RNA expression.
This table summarizes LINC00858 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 12. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00858. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00858 shows higher tumor expression in COAD, LUAD, STAD, LUSC, HNSC and BLCA. The COAD box plot shows higher LINC00858 RNA expression in tumor versus normal tissue (log2 FC = +1.285, t-test p < 0.001).
This table shows molecular features associated with LINC00858 in patient tissues and cancer cell lines. In patient samples, LINC00858 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
