LINC00653

Across TCGA patient cohorts, LINC00653 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,183 significant associations in total. GBM shows the largest number of these associations.

The most reproducible LINC00653-associated proteins across cancer lineages are MRE11, XRN2, and PCIF1. Each is linked with LINC00653 in more than 5 cancer types. Because this analysis shows association rather than direction, both LINC00653-to-partner and partner-to-LINC00653 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LINC00653 versus MRE11 in COAD, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00653→partner) and Y-score (partner→LINC00653) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MRE11 →	+0.395	+0.570	<.001	<.001	3	6
GBM	XRN2 →	+0.223	+0.395	.003	.002	3	6
GBM	PCIF1 →	+0.311	+0.431	<.001	<.001	3	6
COAD	PDS5B →	+0.375	+0.684	<.001	<.001	3	6
HNSC	MAP7D1_S70 →	-0.652	-0.644	.002	.001	3	5
BRCA	BRD3_S263 →	+0.454	+0.709	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,183 associations by consensus.

LINC00653 vs MRE11 — COAD

Explore this scatter interactively →