Q-omics provides the consensus-scored LINC00638 profile across patient tissues and cancer cell-line models. LINC00638 expression is associated with patient survival in 26 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, LINC00638 is differentially expressed in 13, with the highest sampling consensus in HNSC. Additionally, LINC00638 RNA expression shows 17,758 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight COAD, HNSC, and ACC as cancer lineages where LINC00638 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00638 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00638 survival associations across molecular data types. LINC00638 RNA expression shows survival associations in the most cancer types (26). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00638 RNA expression–survival associations across cancer types. High LINC00638 expression shows unfavorable associations in COAD, ACC, MESO, BLCA and READ, but favorable associations in UVM. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify COAD as the clearest survival context for LINC00638 RNA expression.
This table summarizes LINC00638 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 13. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00638. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00638 shows lower tumor expression in THCA and higher tumor expression in HNSC, LUAD, KIRP, LIHC and COAD. The HNSC box plot shows higher LINC00638 RNA expression in tumor versus normal tissue (log2 FC = +0.506, t-test p < 0.001).
This table shows molecular features associated with LINC00638 in patient tissues and cancer cell lines. In patient samples, LINC00638 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set.
