LINC00638

Across TCGA pan-cancer cohorts, LINC00638 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated LINC00638 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher LINC00638 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00638 expression acts as an unfavorable survival marker, although some lineages such as UVM and BRCA show a favorable association.

COAD, UVM, and ACC are the cancer types where LINC00638 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.379	0.589	<.001	99	view →
UVM	OS	Tertile	II,III,IV	0.917	0.366	<.001	71	view →
ACC	DFS	Quartile	All	0.285	0.730	.001	45	view →
MESO	DFS	Quartile	III,IV	0.222	0.557	<.001	43	view →
BLCA	DFS	Tertile	IV	0.118	0.307	.007	41	view →
READ	OS	Median	All	0.526	0.835	.002	41	view →
BRCA	DFS	Median	IV	0.754	0.342	.002	34	view →
UCS	DFS	Median	All	0.388	0.173	.007	32	view →
DLBC	DFS	Median	All	0.858	0.329	.004	31	view →
SKCM	DFS	Median	III,IV	0.340	0.178	.001	30	view →
CESC	OS	Tertile	All	0.727	0.884	.004	28	view →
KIRC	DFS	Quartile	All	0.816	0.521	<.001	23	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

LINC00638–COAD (DFS)

Open the COAD breakdown →