LINC00477

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LINC00477 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LINC00477-associated genes across cancer lineages are Notch1, PKC-b-II_pS660, and Annexin-1. Each is linked with LINC00477 in more than 2 cancer types. Because this analysis shows association rather than direction, both LINC00477-to-partner and partner-to-LINC00477 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00477→partner) and Y-score (partner→LINC00477) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECNotch1 →+0.260+3.331<.001.00533
UCECPKC-b-II_pS660 →-0.443-2.459<.001.02032
UCECAnnexin-1 →+0.514+2.827.043.03532
UCECATM →-0.603-2.986.005.03532
COADASNS →+0.913+2.815<.001.03631
UCECKu80 →+0.317+2.820.005.03531
Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

Exploration