LINC00471

Across TCGA patient cohorts, LINC00471 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible LINC00471-associated genes across cancer lineages are TBC1D3C, CTHRC1P1, and OR8S21P. Each is linked with LINC00471 in more than 1 cancer types. Because this analysis shows association rather than direction, both LINC00471-to-partner and partner-to-LINC00471 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TBC1D3C grouped by LINC00471-low versus LINC00471-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00471→partner) and Y-score (partner→LINC00471) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TBC1D3C →	+0.028	+4.979	<.001	.009	3	1
UCEC	CTHRC1P1 →	+0.244	+4.694	<.001	.007	3	1
UCEC	OR8S21P →	+0.409	+4.484	<.001	.009	3	1
BRCA	DEFB108E →	+0.108	+8.055	<.001	.007	3	1
LUSC	RNU6-1312P →	+0.261	+7.924	<.001	.008	3	1
LUSC	RNU6-508P →	+0.269	+7.924	.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

TBC1D3C by LINC00471 expression — SKCM

Explore this box plot interactively →