Q-omics provides the consensus-scored DEFB108E profile across patient tissues and cancer cell-line models. DEFB108E expression is associated with patient survival in 4 of 34 cancer types, with the highest sampling consensus in BLCA. Additionally, DEFB108E RNA expression shows 9,763 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight BLCA, and TGCT as cancer lineages where DEFB108E shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes DEFB108E survival associations across molecular data types. DEFB108E RNA expression shows survival associations in the most cancer types (4). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

DEFB108E data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	4	BLCA (45)	view →

This table ranks reproducible DEFB108E RNA expression–survival associations across cancer types. High DEFB108E expression shows unfavorable associations in BLCA, STAD, LGG and GBM. The BLCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .016). Together, the overview and detailed table identify BLCA as the clearest survival context for DEFB108E RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.159	0.625	.016	45	view →
STAD	OS	Tertile	IV	0.075	0.496	.013	27	view →
LGG	OS	Tertile	All	0.436	0.912	<.001	24	view →
GBM	OS	Tertile	All	0.126	0.415	.015	18	view →

Pink = unfavorable, green = favorable. all 4 lineages →

DEFB108E-BLCA (DFS)

Kaplan–Meier survival curve for DEFB108E RNA expression in BLCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with DEFB108E in patient tissues and cancer cell lines. In patient samples, DEFB108E shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	9,763	TGCT (4569)	view →
Function (RNA)	5,678	STAD (5012)	view →