DEFB108E

Across TCGA pan-cancer cohorts, DEFB108E RNA is linked to patient survival in 4 of 34 cancer types, making it the most broadly survival-associated DEFB108E data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher DEFB108E RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated DEFB108E expression acts as an unfavorable survival marker.

BLCA, STAD, and LGG are the cancer types where DEFB108E RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.159	0.625	.016	45	view →
STAD	OS	Tertile	IV	0.075	0.496	.013	27	view →
LGG	OS	Tertile	All	0.436	0.912	<.001	24	view →
GBM	OS	Tertile	All	0.126	0.415	.015	18	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

DEFB108E–BLCA (DFS)

Open the BLCA breakdown →