DEFB108E

Across TCGA patient cohorts, DEFB108E RNA expression is significantly associated with the go_rna of many other GO terms, with 5,678 significant associations in total. STAD shows the largest number of these associations.

The most reproducible DEFB108E-associated GO terms across cancer lineages are Positive regulation of peptidase activity, Methylation, and Macromolecule methylation. Each is linked with DEFB108E in more than 4 cancer types. Because this analysis shows association rather than direction, both DEFB108E-to-partner and partner-to-DEFB108E results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of peptidase activity grouped by DEFB108E-low versus DEFB108E-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB108E→partner) and Y-score (partner→DEFB108E) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of peptidase activity →	+0.123	+0.053	<.001	<.001	3	5
STAD	Methylation →	+0.129	+0.060	<.001	<.001	3	5
STAD	Macromolecule methylation →	+0.131	+0.050	<.001	<.001	3	5
STAD	Regulation of exocytosis →	+0.096	+0.054	<.001	<.001	3	4
STAD	Organic hydroxy compound biosynthetic process →	+0.083	+0.054	<.001	<.001	3	4
STAD	Negative regulation of cell projection organization →	+0.094	+0.053	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,678 associations by consensus.

Positive regulation of peptidase activity by DEFB108E expression — STAD

Explore this box plot interactively →