LINC00471

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC00471 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated LINC00471 data layer compared with 3 for mutation status.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher LINC00471 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00471 expression acts as an unfavorable survival marker, although some lineages such as COAD and UVM show a favorable association.

KIRC, ACC, and KICH are the cancer types where LINC00471 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCDFSQuartileIV0.2870.723.00267view →
ACCDFSTertileAll0.3760.790<.00164view →
KICHOSQuartileIII,IV0.1940.855.00457view →
BLCADFSQuartileIV0.1010.330.00528view →
KIRPDFSMedianAll0.3810.713.02419view →
UCECDFSTertileAll0.8170.890.01518view →
COADOSQuartileIV0.9050.474.00216view →
UVMOSTertileII,III,IV0.8840.587.02314view →
LIHCOSTertileAll0.6670.830.00413view →
UCSDFSQuartileII,III,IV0.7210.226.00912view →
MESOOSTertileII,III,IV0.4850.288.01511view →
READDFSMedianII,III,IV0.7680.567.01811view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

LINC00471–KIRC (DFS)

Kaplan–Meier survival curve for LINC00471 RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration