LINC00445

Across TCGA patient cohorts, LINC00445 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,689 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00445-associated GO terms across cancer lineages are Osteoblast differentiation, Epithelial to mesenchymal transition, and Heart morphogenesis. Each is linked with LINC00445 in more than 8 cancer types. Because this analysis shows association rather than direction, both LINC00445-to-partner and partner-to-LINC00445 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Osteoblast differentiation grouped by LINC00445-low versus LINC00445-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00445→partner) and Y-score (partner→LINC00445) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Osteoblast differentiation →	+0.070	+0.065	<.001	<.001	3	9
STAD	Epithelial to mesenchymal transition →	+0.071	+0.063	<.001	<.001	3	8
STAD	Heart morphogenesis →	+0.059	+0.057	<.001	<.001	3	8
STAD	Axon extension →	+0.067	+0.070	<.001	<.001	3	8
STAD	Negative regulation of growth →	+0.063	+0.069	<.001	<.001	3	8
TGCT	Positive regulation of animal organ morphogenesis →	+0.071	+0.258	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,689 associations by consensus.

Osteoblast differentiation by LINC00445 expression — STAD

Explore this box plot interactively →