LINC00445

Across TCGA pan-cancer cohorts, LINC00445 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated LINC00445 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher LINC00445 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00445 expression acts as an unfavorable survival marker, although some lineages such as SARC and LUAD show a favorable association.

BLCA, STAD, and DLBC are the cancer types where LINC00445 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Tertile	All	0.285	0.621	<.001	144	view →
STAD	OS	Tertile	All	0.272	0.452	.009	84	view →
DLBC	DFS	Tertile	All	0.338	0.795	.010	58	view →
KICH	DFS	Tertile	All	0.591	1.000	.009	27	view →
BRCA	OS	Tertile	IV	0.332	0.691	.010	27	view →
SARC	DFS	Tertile	All	0.662	0.473	.004	18	view →
CESC	OS	Tertile	IV	0.095	0.592	.004	18	view →
LIHC	OS	Tertile	II,III,IV	0.158	0.626	.034	18	view →
LUAD	DFS	Tertile	II,III,IV	0.635	0.362	.038	12	view →
READ	DFS	Tertile	III,IV	0.269	0.744	.025	9	view →
HNSC	OS	Tertile	II,III,IV	0.302	0.377	.027	9	view →
SKCM	OS	Tertile	II,III,IV	0.359	0.347	.023	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

LINC00445–BLCA (DFS)

Open the BLCA breakdown →