LINC00400

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC00400 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated LINC00400 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher LINC00400 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00400 expression acts as an unfavorable survival marker, although some lineages such as BLCA and ACC show a favorable association.

LUAD, READ, and UCS are the cancer types where LINC00400 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
LUADDFSTertileIV0.3420.893<.00178view →
READDFSTertileIII,IV0.2220.765.00157view →
UCSDFSTertileIII,IV0.1780.469.01954view →
COADDFSTertileAll0.2840.706<.00148view →
BLCADFSTertileIII,IV0.8820.426.02142view →
STADDFSTertileAll0.3830.570.00339view →
MESOOSTertileIV0.0360.602<.00136view →
BRCADFSTertileAll0.1401.000.00136view →
LIHCOSTertileII,III,IV0.1630.719<.00136view →
UCECOSTertileAll0.8360.933<.00136view →
THCAOSTertileAll0.5390.958<.00133view →
PRADDFSTertileAll0.7360.890.00912view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

LINC00400–LUAD (DFS)

Kaplan–Meier survival curve for LINC00400 RNA-high vs -low samples in LUAD.

Open the LUAD breakdown →

Exploration