Across TCGA pan-cancer cohorts, LINC00400 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of LINC00400’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where LINC00400 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types LINC00400 is over-expressed in tumor.
BRCA are the cancer types where LINC00400 tumor–normal differential expression is most reproducible.