long intergenic non-protein coding RNA 400Genealiases: []
Q-omics provides the consensus-scored LINC00400 profile across patient tissues and cancer cell-line models. LINC00400 expression is associated with patient survival in 14 of 34 cancer types, with the highest sampling consensus in LUAD. Among the 18 cancer types available for tumor–normal comparison, LINC00400 is differentially expressed in 1, with the highest sampling consensus in BRCA. Additionally, LINC00400 RNA expression shows 7,595 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight LUAD, BRCA, and TGCT as cancer lineages where LINC00400 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00400 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00400 survival associations across molecular data types. LINC00400 RNA expression shows survival associations in the most cancer types (14). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00400 RNA expression–survival associations across cancer types. High LINC00400 expression shows unfavorable associations in LUAD, READ, UCS, COAD and STAD, but favorable associations in BLCA. The LUAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LUAD as the clearest survival context for LINC00400 RNA expression.
This table summarizes LINC00400 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 1. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00400. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00400 shows higher tumor expression in BRCA. The BRCA box plot shows higher LINC00400 RNA expression in tumor versus normal tissue (log2 FC = +0.042, t-test p = .004).
This table shows molecular features associated with LINC00400 in patient tissues and cancer cell lines. In patient samples, LINC00400 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
