LINC00365

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, LINC00365 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated LINC00365 data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher LINC00365 RNA is associated with better overall survival. In most high-consensus cancer types, elevated LINC00365 expression acts as an unfavorable survival marker, although some lineages such as UVM and UCS show a favorable association.

UVM, LGG, and ESCA are the cancer types where LINC00365 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UVMOSTertileII,III,IV0.8280.356<.00172view →
LGGOSMedianAll0.3500.504<.00154view →
ESCAOSTertileIII,IV0.3450.690<.00143view →
UCSDFSQuartileAll0.5170.137.00628view →
THCADFSTertileII,III,IV0.5040.939<.00126view →
THYMOSTertileII,III,IV0.8461.000.00216view →
DLBCDFSQuartileIII,IV0.1370.800<.00115view →
MESOOSMedianIV0.9280.404.0159view →
SKCMDFSMedianAll0.6760.544.0049view →
COADOSQuartileAll0.7370.885.0357view →
READOSQuartileAll0.8200.592.0237view →
HNSCDFSTertileIV0.6110.483.0306view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

Exploration