long intergenic non-protein coding RNA 365Genealiases: []
Q-omics provides the consensus-scored LINC00365 profile across patient tissues and cancer cell-line models. LINC00365 expression is associated with patient survival in 21 of 34 cancer types, with the highest sampling consensus in UVM. Among the 18 cancer types available for tumor–normal comparison, LINC00365 is differentially expressed in 11, with the highest sampling consensus in LUAD. Additionally, LINC00365 RNA expression shows 12,687 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight UVM, LUAD, and TGCT as cancer lineages where LINC00365 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00365 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00365 survival associations across molecular data types. LINC00365 RNA expression shows survival associations in the most cancer types (21). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00365 RNA expression–survival associations across cancer types. High LINC00365 expression shows unfavorable associations in LGG, ESCA, THCA and THYM, but favorable associations in UVM and UCS. The UVM Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p < 0.001). Together, the overview and detailed table identify UVM as the clearest survival context for LINC00365 RNA expression.
This table summarizes LINC00365 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00365. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00365 shows lower tumor expression in LUAD, LUSC and KIRC and higher tumor expression in HNSC, COAD and BRCA. The LUAD box plot shows higher LINC00365 RNA expression in normal versus tumor tissue (log2 FC = −0.679, t-test p < 0.001).
This table shows molecular features associated with LINC00365 in patient tissues and cancer cell lines. In patient samples, LINC00365 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
