LINC00353

Across TCGA patient cohorts, LINC00353 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,874 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00353-associated GO terms across cancer lineages are Positive regulation of protein kinase activity, Establishment or maintenance of cell polarity, and Regulation of protein ubiquitination. Each is linked with LINC00353 in more than 4 cancer types. Because this analysis shows association rather than direction, both LINC00353-to-partner and partner-to-LINC00353 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein kinase activity grouped by LINC00353-low versus LINC00353-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00353→partner) and Y-score (partner→LINC00353) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of protein kinase activity →	+0.101	+0.041	<.001	<.001	3	5
STAD	Establishment or maintenance of cell polarity →	+0.121	+0.044	<.001	<.001	3	5
STAD	Regulation of protein ubiquitination →	+0.135	+0.050	<.001	<.001	3	5
STAD	Telomerase RNA localization →	+0.127	+0.037	<.001	<.001	3	4
STAD	Regulation of binding →	+0.128	+0.045	<.001	<.001	3	4
STAD	Regulation of DNA binding →	+0.116	+0.044	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,874 associations by consensus.

Positive regulation of protein kinase activity by LINC00353 expression — STAD

Explore this box plot interactively →