LINC00353

Across TCGA pan-cancer cohorts, LINC00353 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated LINC00353 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher LINC00353 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated LINC00353 expression acts as an unfavorable survival marker, although some lineages such as LAML show a favorable association.

BLCA, CHOL, and LIHC are the cancer types where LINC00353 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	IV	0.230	0.606	.002	132	view →
CHOL	OS	Tertile	All	0.089	0.746	<.001	117	view →
LIHC	OS	Tertile	II,III,IV	0.514	0.751	.001	72	view →
SKCM	DFS	Tertile	All	0.058	0.757	<.001	54	view →
LGG	DFS	Tertile	All	0.139	0.416	<.001	42	view →
TGCT	DFS	Tertile	II,III,IV	0.088	0.917	.010	36	view →
KIRP	OS	Tertile	All	0.384	0.696	<.001	36	view →
COAD	OS	Tertile	II,III,IV	0.183	0.788	.007	27	view →
UCEC	OS	Tertile	All	0.200	0.686	.005	24	view →
UCS	OS	Tertile	All	0.178	0.584	.036	18	view →
LUSC	OS	Tertile	III,IV	0.264	0.670	.013	18	view →
LAML	DFS	Tertile	All	0.505	0.394	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

LINC00353–BLCA (OS)

Open the BLCA breakdown →