LINC00349

Across TCGA patient cohorts, LINC00349 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,168 significant associations in total. STAD shows the largest number of these associations.

The most reproducible LINC00349-associated GO terms across cancer lineages are Response to alcohol, Negative regulation of epithelial cell proliferation, and Negative regulation of DNA metabolic process. Each is linked with LINC00349 in more than 5 cancer types. Because this analysis shows association rather than direction, both LINC00349-to-partner and partner-to-LINC00349 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to alcohol grouped by LINC00349-low versus LINC00349-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LINC00349→partner) and Y-score (partner→LINC00349) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Response to alcohol →	+0.078	+0.044	<.001	<.001	3	6
STAD	Negative regulation of epithelial cell proliferation →	+0.076	+0.046	<.001	<.001	3	6
STAD	Negative regulation of DNA metabolic process →	+0.091	+0.048	<.001	<.001	3	6
STAD	Negative regulation of binding →	+0.098	+0.047	<.001	<.001	3	6
STAD	Nuclear export →	+0.115	+0.045	<.001	<.001	3	6
STAD	Regulation of proteasomal protein catabolic process →	+0.114	+0.052	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,168 associations by consensus.

Response to alcohol by LINC00349 expression — STAD

Explore this box plot interactively →