LINC00349

Across TCGA pan-cancer cohorts, LINC00349 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated LINC00349 data layer.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher LINC00349 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated LINC00349 expression acts as an unfavorable survival marker, although some lineages such as BLCA and SKCM show a favorable association.

COAD, THCA, and BLCA are the cancer types where LINC00349 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	0.170	0.790	.002	45	view →
THCA	OS	Tertile	II,III,IV	0.646	0.924	<.001	39	view →
BLCA	OS	Tertile	II,III,IV	1.000	0.594	.011	36	view →
LUAD	OS	Tertile	II,III,IV	0.156	0.677	.012	24	view →
GBM	OS	Tertile	All	0.064	0.422	<.001	18	view →
THYM	DFS	Tertile	All	0.091	0.884	<.001	18	view →
PCPG	DFS	Tertile	All	0.070	0.936	<.001	18	view →
LUSC	OS	Tertile	III,IV	0.185	0.570	.035	18	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	9	view →
SKCM	DFS	Tertile	All	0.267	0.177	.033	6	view →
KIRC	OS	Tertile	All	0.472	0.676	.018	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

LINC00349–COAD (DFS)

Open the COAD breakdown →