LIMS4

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LIMS4 RNA expression is significantly associated with the protein abundance of many other proteins, with 2,869 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LIMS4-associated proteins across cancer lineages are SIK3_S647, SP100_S171, and STARD3NL_S39. Each is linked with LIMS4 in more than 1 cancer types. Because this analysis shows association rather than direction, both LIMS4-to-partner and partner-to-LIMS4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LIMS4 versus SIK3_S647 in BRCA, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LIMS4→partner) and Y-score (partner→LIMS4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCASIK3_S647 →-0.803-0.056.003.00132
GBMSP100_S171 →+0.561+0.013.005.00332
OVSTARD3NL_S39 →+0.873+0.815<.001<.00132
OVCETN2_S20 →-0.642-0.589.002<.00132
OVCOL9A1 →+0.697+0.941<.001<.00132
OVCRYBG3 →+0.312+0.670.002<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,869 associations by consensus.

LIMS4 vs SIK3_S647 — BRCA

Per-sample scatter of LIMS4 vs SIK3_S647 in BRCA (Pearson r = -0.39).

Explore this scatter interactively →

Exploration