LHX6

Across TCGA patient cohorts, LHX6 protein abundance is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible LHX6-associated genes across cancer lineages are OR52N2, CFL1P6, and GAPDHP74. Each is linked with LHX6 in more than 1 cancer types. Because this analysis shows association rather than direction, both LHX6-to-partner and partner-to-LHX6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LHX6 versus OR52N2 in BRCA, with a Pearson correlation of -0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LHX6→partner) and Y-score (partner→LHX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	OR52N2 →	-0.220	-1.050	.006	.008	2	1
BRCA	CFL1P6 →	-0.426	-1.050	.005	.008	2	1
BRCA	GAPDHP74 →	-0.250	-1.050	.006	.008	2	1
BRCA	MIR6129 →	-1.143	-1.050	<.001	.008	2	1
BRCA	ACAD10 →	-0.428	-0.483	.004	.002	1	1
BRCA	LINC02659 →	-0.099	-1.050	<.001	.008	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

LHX6 vs OR52N2 — BRCA

Explore this scatter interactively →