Across TCGA patient cohorts, LHX1-DT RNA expression is significantly associated with the go_rna of many other GO terms, with 6,934 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible LHX1-DT-associated GO terms across cancer lineages are Oviduct development, Metanephric part of ureteric bud development, and Primitive streak formation. Each is linked with LHX1-DT in more than 15 cancer types. Because this analysis shows association rather than direction, both LHX1-DT-to-partner and partner-to-LHX1-DT results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LHX1-DT→partner) and Y-score (partner→LHX1-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Oviduct development →	-0.124	-0.451	<.001	<.001	2	16
MESO	Metanephric part of ureteric bud development →	-0.088	-0.586	<.001	<.001	3	12
HNSC	Primitive streak formation →	-0.090	-0.715	<.001	<.001	3	11
TGCT	Positive regulation of fibroblast proliferation →	+0.041	+0.842	<.001	<.001	3	11
TGCT	Epithelial to mesenchymal transition involved in endocardial cushion formation →	+0.107	+1.338	<.001	<.001	3	10
STAD	Cytokinetic process →	+0.085	+0.222	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,934 associations by consensus.

Exploration

LHX1-DT survival (RNA) · tumor vs normal (RNA) · all LHX1-DT data types