LHFPL6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, LHFPL6 mutation is significantly associated with the RNA expression of many other genes, with 1,373 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LHFPL6-associated genes across cancer lineages are MIR4510, BRK1P1, and RN7SL248P. Each is linked with LHFPL6 in more than 1 cancer types. Because this analysis shows association rather than direction, both LHFPL6-to-partner and partner-to-LHFPL6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LHFPL6→partner) and Y-score (partner→LHFPL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCMIR4510 →+0.403+6.342<.001.00132
HNSCBRK1P1 →+0.332+5.015<.001.00932
UCECRN7SL248P →+0.059+3.137<.001.00532
SKCMPCYT1B-AS1 →+0.077+3.555.002.00432
BLCARNU6-770P →+0.500+4.429<.001.00632
UCECMRPL49 →+0.528+3.923.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,373 associations by consensus.

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