LEMD3

Across TCGA patient cohorts, LEMD3 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,819 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible LEMD3-associated proteins across cancer lineages are SIN3A, HNRNPLL, and IRF2BP1. Each is linked with LEMD3 in more than 4 cancer types. Because this analysis shows association rather than direction, both LEMD3-to-partner and partner-to-LEMD3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, LEMD3 versus SIN3A in HNSC, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (LEMD3→partner) and Y-score (partner→LEMD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SIN3A →	+0.222	+0.550	<.001	.001	3	5
LSCC	HNRNPLL →	+0.217	+0.422	<.001	<.001	3	5
HNSC	IRF2BP1 →	+0.339	+0.711	<.001	.001	3	5
GBM	HCFC1 →	+0.286	+0.346	<.001	<.001	3	5
LSCC	POGZ →	+0.254	+0.415	<.001	<.001	3	5
GBM	POLR2A →	+0.221	+0.274	.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,819 associations by consensus.

LEMD3 vs SIN3A — HNSC

Explore this scatter interactively →