Across TCGA patient cohorts, LEMD1 mutation is significantly associated with the RNA expression of many other genes, with 73 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LEMD1-associated genes across cancer lineages are ATF4P1, RNA5SP422, and RNU6-1169P. Each is linked with LEMD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LEMD1-to-partner and partner-to-LEMD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LEMD1→partner) and Y-score (partner→LEMD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATF4P1 →	+0.072	+3.132	<.001	.003	3	2
UCEC	RNA5SP422 →	+1.186	+2.671	<.001	.005	3	2
SKCM	RNU6-1169P →	+0.250	+3.947	<.001	.002	3	2
SKCM	KCNIP4-IT1 →	+0.010	+3.018	<.001	.009	3	1
UCEC	YTHDF3-AS1 →	+0.893	+3.223	<.001	.009	3	1
UCEC	IGLL4P →	+0.584	+2.671	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 73 associations by consensus.

Exploration

LEMD1 survival (RNA) · tumor vs normal (RNA) · all LEMD1 data types