Across TCGA patient cohorts, LDLRAD1 mutation is significantly associated with the RNA expression of many other genes, with 54 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LDLRAD1-associated genes across cancer lineages are RNU6-89P, RNA5SP407, and MTND5P27. Each is linked with LDLRAD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both LDLRAD1-to-partner and partner-to-LDLRAD1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LDLRAD1→partner) and Y-score (partner→LDLRAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RNU6-89P →	+0.487	+5.683	<.001	.004	3	2
LUSC	RNA5SP407 →	+0.633	+7.924	<.001	.008	3	2
SKCM	MTND5P27 →	+0.012	+4.302	<.001	.007	3	2
BRCA	MIR7159 →	+0.452	+5.317	<.001	.006	3	1
BRCA	DNM1P28 →	+0.086	+5.288	.001	.006	3	1
SKCM	LINC02272 →	+0.032	+4.302	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 54 associations by consensus.

Exploration

LDLRAD1 survival (RNA) · tumor vs normal (RNA) · all LDLRAD1 data types