LDHAL6B

Across TCGA patient cohorts, LDHAL6B mutation is significantly associated with the RNA expression of many other genes, with 2,181 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LDHAL6B-associated genes across cancer lineages are MIR4771-2, RNASEK, and RNA5SP64. Each is linked with LDHAL6B in more than 1 cancer types. Because this analysis shows association rather than direction, both LDHAL6B-to-partner and partner-to-LDHAL6B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR4771-2 grouped by LDHAL6B-low versus LDHAL6B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LDHAL6B→partner) and Y-score (partner→LDHAL6B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MIR4771-2 →	+0.510	+3.855	<.001	.002	3	2
UCEC	RNASEK →	+0.423	+3.743	<.001	<.001	3	2
SKCM	RNA5SP64 →	+0.230	+4.199	<.001	.009	3	2
UCEC	ATP5F1A →	+0.442	+3.000	.003	.001	3	2
UCEC	CXCL13 →	+1.234	+3.906	.006	<.001	3	2
UCEC	REEP4 →	+0.458	+2.606	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,181 associations by consensus.

MIR4771-2 by LDHAL6B expression — SKCM

Explore this box plot interactively →