LDHA

Across TCGA cell cohorts, LDHA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,877 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible LDHA-associated GO terms across cancer lineages are Carbohydrate biosynthetic process, Spindle elongation, and Purine-containing compound catabolic process. Each is linked with LDHA in more than 12 cancer types. Because this analysis shows association rather than direction, both LDHA-to-partner and partner-to-LDHA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Carbohydrate biosynthetic process grouped by LDHA-low versus LDHA-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (LDHA→partner) and Y-score (partner→LDHA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Carbohydrate biosynthetic process →	+0.074	+1.028	<.001	<.001	3	13
OESOPHAGUS	Spindle elongation →	+0.224	+1.152	.008	<.001	3	12
OVARY	Purine-containing compound catabolic process →	+0.074	+1.378	.001	.001	3	12
SOFT_TISSUE	Maintenance of protein location in mitochondrion →	+0.167	+0.745	<.001	.002	3	12
BREAST	Peptidyl-lysine oxidation →	+1.073	+0.759	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Positive regulation of chromosome condensation →	+0.181	+0.924	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,877 associations by consensus.

Carbohydrate biosynthetic process by LDHA expression — SOFT_TISSUE

Explore this box plot interactively →