Across TCGA patient cohorts, LCE5A mutation is significantly associated with the RNA expression of many other genes, with 447 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible LCE5A-associated genes across cancer lineages are UBTFL3, UBE2Q2P9, and GTF3C6P3. Each is linked with LCE5A in more than 1 cancer types. Because this analysis shows association rather than direction, both LCE5A-to-partner and partner-to-LCE5A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (LCE5A→partner) and Y-score (partner→LCE5A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	UBTFL3 →	+0.079	+7.954	<.001	.008	3	2
COAD	UBE2Q2P9 →	+0.167	+4.516	.008	.009	3	2
UCEC	GTF3C6P3 →	+0.243	+2.303	.002	.009	3	2
SKCM	TBCC →	+0.522	+3.478	.001	.002	3	2
UCEC	RN7SKP192 →	+0.212	+2.646	.001	.009	3	2
UCEC	SYPL1P1 →	+0.179	+3.538	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 447 associations by consensus.

Exploration

LCE5A survival (RNA) · tumor vs normal (RNA) · all LCE5A data types